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Thyroid Medications Stopped Working?- Heres 10 Reasons Why Your Thyroid Medication Has Stopped Working

Video transcript

Do you take thyroid medications like Synthroid, Levothyroxine, Cytomel Armour and no matter what changes your doctor makes to the dosage, you still struggle with thyroid symptoms? Does it feel like your Thyroid medication has stopped working? If you answered YES to either of these questions, stay tuned…. this video is specifically for you!

I’m Dr Hagmeyer and I am the clinic director at where we specialize in helping patients from all over the world find answers and solutions to some of the most challenging and chronic health problems.

Every morning, I get anywhere from 20-30 new emails from people who have being diagnosed with thyroid disease, most of them have been on thyroid medications for months and years and they still don’t feel better, they still suffer with all the symptoms of low thyroid, despite taking thyroid hormone replacement.

Still Suffering with Thyroid Symptoms? It’s a Bit More Than Chasing Your Thyroid Medication Or Changing Dosage.

Before I get into this video, I know on the surface that it makes sense that if we could just raise those low thyroid levels to that normal range, that would fix all your problems, everything would fall into place, the weight will just melt off your body, the brain fog, anxiety and depression would vanish and you would jump out of bed in the morning feeling refreshed!

Unfortunately, If you took a survey of all the doctors who treat patients with thyroid hormones and asked them how many of your patients feel great, now that their thyroid hormone levels are within normal range- you would find an incredible low number of patients who are happy and would report feeling good. Most still suffer with unresolved thyroid symptoms despite normal thyroid levels.

Start Feeling Better Today!

So, let me peel back some of the reasons why it feels like your thyroid medication has stopped working and give you some of the most important areas of your health that you should start focusing in on. If you Do these things, I promise you will start feeling better.

Thyroid Medications Stopped Working?- Heres 10 Reasons Why You feel Terrible Again....

Why It Feels Like Your Thyroid Medication is No Longer Working

Reason #1 Your Thyroid Medication Feels Like It Has Stopped Working- You Have One or More Vitamin Deficiencies

Most patients with Thyroid disease find themselves with many vitamin deficiencies not only vitamin D or B12. While I highly doubt that a deficiency in any one vitamin is causing your problems, Chances are you have multiple vitamin deficiencies and it is the combined effect of these vitamin deficiencies that are contributing to your low thyroid symptoms.

Some of the most deficiencies seen in thyroid disease include Vitamin A, Vitamin D, Vitamin K, Zinc, Selenium, Iron, and your B- complex vitamins (B2, B3, B6, Folate, B12). Selenium and zinc help convert T4 into T3, Iron, Zinc, Vitamin D, and your B vitamins (B2,3,6,12) all help in making Thyroid hormones and Vitamin A is needed for improving cellular sensitivity.

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Reason #2 Your Thyroid Medication Feels Like It Has Stopped Working, You Have A Sensitivity or Allergy to the Binders Fillers Found In Your Thyroid Medication.

Many people taking thyroid medications suffer with chemical sensitivities, food allergies, and food intolerances. For those who do have sensitivities, the most common ones are gluten, dairy, corn. You may also be sensitive to binders, fillers, heavy metals. These are commonly found in thyroid medication.

Gluten sensitivity and Celiac disease often goes hand-in-hand with thyroid disease and Hashimotos thyroiditis. Cytomel, which is a T3 Thyroid preparation made by Pfizer, uses a starch which is used to bind the medication together- The starches are made from wheat (gluten) and Corn. Levothyroxine is a T4 Thyroid replacement, it also contains gluten, Dairy, corn, Sugar and all kinds of Dyes.

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Now you might be thinking… aluminum in my Thyroid medication…. Isn’t that bad for the brain? You would be correct Or you might be thinking artificial colors in my Thyroid medication? red #40, blue #1 and yellow #10- how can that be good for me?

Or perhaps you were just tested for food allergies like wheat, dairy and corn and you tested positive for these. Now, I want you to imagine if you unknowingly have problems with any of these binders, fillers, artificial colors, heavy metals, sugars, etc ….what if you started taking Thyroid medications and didn’t know you had an allergy or sensitivity. Do you think this might make you feel worse?

Worst case scenario, you could flare up your immune system causing more damage to your thyroid gland and at the very least develop some new symptoms that you may not have had before things like headaches, fatigue, brain fog, weight gain, congestion, breathing problems and other symptoms.

Reason #3 Your Thyroid Medication Feels Like It Has Stopped Working You Have a Gut issue.

Have ever thought that about your digestion and how it might be linked to poor thyroid function? Let me explain a few important things when it comes to digestion, gut health and thyroid function…. If you can’t break down your foods because you have poor gallbladder function, poor pancreatic function or you don’t have sufficient amounts of Hydrochloric acid (HCL) in your stomach (again all common problems in people with thyroid disease and Hashimotos) then you are not going to optimally extract your nutrients from the foods you eat.

If you have a gut issue- be sure to watch the video below.

Nutrient deficiencies, (depending on the nutrient you are deficient in) can lead to poor T4 to T3 conversion, poor thyroid hormone production, and lastly poor Thyroid cellular function. This is problem #1, The 2nd problem we often see in our patients with Thyroid disease, is gut infections. This might be a yeast overgrowth, it might be a bacterial overgrowth (SIBO) or it might be infection like Pylori. Many of these infections are caused by long standing problems with insufficient production of proteolytic digestive enzymes or the Hydrochloric acid (HCL) I mentioned just a moment ago. Before I move onto the next area, I want to say one more thing here related to digestion and thyroid disease and this is really important if you take a T4 Thyroid replacement like Synthroid, or Levothyroxine. When you take Synthroid or Levothyroxine you are taking a T4 only hormone preparation.

What this means is that your gut, still needs to take this T4 and convert it into T3 thyroid hormones. One of the most common patterns I see in my thyroid patients is Low T3 levels and one of the main reasons for this low T3 is poor digestion or infection. Thyroid Under-conversion- otherwise known as Low T3.

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Reason #4 Your Thyroid Medication Feels Like It Has Stopped Working, You Have untreated or undiagnosed Adrenal dysfunction/Adrenal Fatigue . 

Chronic Stress is no stranger to those who suffer with thyroid disease. But it’s the stress hormones like cortisol and DHEA that have a tremendous impact on thyroid function. Too much cortisol, too little cortisol or too little DHEA pose huge problems for proper thyroid function.

If you have weakened adrenals, due to chronic stress, fluctuating blood sugar levels, or inflammation, you’ll need to support your adrenals.

Remember your adrenals are your FIGHT/FLIGHT glands- any amount of stress on them can have far ranging effects on the body, including digestion.

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Reason #5 Your Thyroid Medication Feels Like It Has Stopped Working- You have a Toxic, overworked and stressed out liver.

Your liver is involved in over 300 different functions. Liver filters blood from the digestive system, its involved in Cholesterol production, it produces bile that helps eliminate toxins from the body, it processes hormones, it cleans and purifies the blood, it produces all kinds of enzymes and the list goes on and on. It’s also the place where 60% of that T4 thyroid hormone is converted into active T3 Thyroid hormones. Many medications people take along side of their thyroid medication, puts additional stress and strain on the liver.

why your thyroid medication has stopped working

Medications like Aspirin, Tylenol, antidepressants, antibiotics, birth control pills, synthetic estrogens like those seen in patches and HRT all tax an overwork your liver- now the icing on the cake is the Standard American Diet… NO wonder we are seeing an increase in thyroid disease and Hashimotos.

One of the things I say over an over with perspective patients is that successful treatment of thyroid disease requires a BIG picture approach. You have to think outside the box!

If it was just your Thyroid, you should be able to take thyroid medication and call it a day. All your problems would be gone.

But my bet is that if you are still watching this video, then you have already started to figure out, there is much more going on than just making thyroid levels look good on paper.

If you are serious about healing your Thyroid gland, you have to understand that you need to heal the Whole body not just the Thyroid.

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Blood Sugar Thyroid Connection- Why Blood Sugar is So Important If You Have Thyroid Disease 4

Reason #6 Your Thyroid Medication Feels Like It Has Stopped Working- You Have High Level of Reverse T3.

The Thyroid gland makes T4, it makes T3 and it makes small amounts of something called Reverse T3. High levels of Reverse T3 can cause Low Thyroid symptoms. Under periods of chronic stress such as low-calorie diets, malnutrition, excessive cortisol production, severe illness, inflammation, your body will take T4 and convert it into Reverse T3.

Here’s the problem, Reverse T3 is not the same as T3. High levels of Reverse T3 bind to the thyroid receptors that are meant for T3. The end result is low thyroid hormone levels. This can happen despite having normal T3 thyroid levels on bloodwork.

If you have a doctor who ran a comprehensive Thyroid panel and you have your Reverse T3 and total T3 levels then you can calculate your T3/Reverse T3 ratio.

If you visit my website, you can plug in your values and you can find out what this ratio is as well as learn more how High levels of Reverse T3 cause Thyroid problems

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  1. 5 Reasons you have High Reverse T3
  2. Why Reverse T3 causes Low Thyroid Function
  3. Why T3/Reverse T3 ratio is important and How To Calculate your T3/Reverse T3 ratio
  4. Stress and The role it has on Reverse T3 levels
  5. How High Reverse T3 Causes Thyroid Problems
  6. How High Reverse T3 will Cause Thyroid Symptoms
  7. Restore Your Thyroid By Lowering Your Reverse T3
  8. T3 Reverse T3 Ratio- How To Calculate It.
  9. High Reverse T3 Levels- 5 Causes Behind Your High RT3 Levels
  10. The Causes Behind Poor Thyroid Conversion. Dr Richard Hagmeyer
  11. 10 Steps To Supporting Your Thyroid Naturally| Dr. Hagmeyer
  12. Why Thyroid Testing Is Misleading

Reason #7 Your Thyroid Medication Feels Like It Has Stopped Working, You have a problem with Thyroid conversion.

Earlier, I mentioned that the thyroid gland makes T4, it makes T3 and it makes a small amount of Reverse T3. T4 is inactive thyroid hormone- it doesn’t do very much, and this is the reason it needs to be converted into T3. T3 is approximately 4x more potent than T4. There are many reasons in which your body does not covert T4 into T3.

If You have low total T3 levels or low Free T3 levels on bloodwork, I recommend that you read some of the articles I have written on the causes of Low T3 and low Free T3.

If you are a person who can’t covert T4 into T3, your doctor will either increase your T4 levels or they will add in another thyroid hormone that contains T3. Usually, it is something Like Cytomel. But guess what, taking additional T3 thyroid hormones, still does not address the root cause of why you are not properly converting T4 into T3.

Here Are A few Reasons You May Not Be Converting T4 into T3 and Have Low T3 Syndrome

Selenium is another important vitamin in that it helps activate the enzymes needed to convert T4 into T3. Iron is required to activate Thyroid peroxidase Enzyme- This is the enzyme that is needed to make Thyroid hormone, Copper and Vitamin C are other is important vitamin needed to make T3 and reduce oxidative stress within the thyroid gland.

Thyroid Medications Stopped Working?- Heres 10 Reasons Why You feel Terrible Again.... 1

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  1. Causes behind Poor Thyroid Conversion
  2. Other Thyroid Patterns that cause Low Thyroid Symptoms

Reason #8 Your Thyroid Medication Feels Like It Has Stopped Working, You have blood sugar problem.

Don’t overlook the importance of Healthy Blood Sugar. 1 in 3 Americans have insulin resistance and don’t know it. Healthy Thyroid Function is absolutely dependent on Healthy blood sugar levels.

Blood Sugar problem are rampant among Americans, but they pose a special problem to those of you suffering with Hypothyroidism and Hashimotos Thyroiditis. It’s important to understand that whether you have high or low blood sugar, you probably have some degree of insulin resistance. Insulin is a fat storing hormone that takes sugar in the blood and shuttles it into the cells for energy. Insulin resistance occurs when the insulin receptors on the cell fail to respond and consequently your blood sugar stays elevated.

Elevated Insulin levels are at the root of many disease processes such as Heart disease, PCOS, Fibroids, Hormonal imbalances, Leptin Resistance, and of course Cancer.

Elevated blood sugar as in the case of Insulin resistance or Diabetes is a contributing factor to thyroid conversion problems. If you have fasting blood sugar levels over 100, elevated triglycerides, low LDH levels- you have a blood sugar problem.

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Reason #9 Your Thyroid Medication Feels Like It Has Stopped Working, You Have Hashimotos disease and don’t Know It.

Hashimoto’s disease is the No. 1 cause of thyroid disease, and it frequently goes undiagnosed. A standard thyroid panel does not test for this so unless your Doctor has ordered a more comprehensive Thyroid it often goes undiagnosed.

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The way Hashimotos is diagnosed is either by ultrasound or by having antibodies tested. There are two antibodies that need testing. One is called TPO ab (thyroid peroxidase) and the other is antithyroglobulin antibodies or TGB antibodies.

Unfortunately, in about 15-20% of the population, these antibodies can still be negative despite having Hashimotos disease. If antibodies are negative and you have problems swallowing or you notice a nodule or lump in your neck, I recommend getting an ultrasound.

There are several reasons to be concerned about nodules and I discuss them in a video titled when you need to be concerned about Thyroid nodules

Reason #10 Your Thyroid Medication Feels Like It Has Stopped Working, You Have Low Thyroid Receptor Sensitivity

While most doctors don’t talk about this as a reason for low thyroid function. Low Thyroid Receptor Sensitivity is an overlooked reason for low thyroid function. When your body is suffering from inflammation, it can “blunt” the sensitivity of receptors on cell membranes that transfer thyroid hormone for the cells to use. It can also reduce the number of those receptors overall- this is called thyroid receptor downregulation.

When the receptors’ sensitivity is blunted and down-regulated, you often have all the symptoms of low thyroid but surprisingly some people have a normal TSH level. A common culprit for this downregulation or blunted receptor sensitivity in addition to systemic inflammation is a vitamin A deficiency, or a Zinc Deficiency.

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Final Thoughts and Take Aways From Today’s video

#1 Thyroid replacement is not a magic bullet, it won’t fix any of the problems I talked about today and this idea that Thyroid replacement is a magic pill has to stop.

#2 Remember, just like the other systems in your body, your thyroid doesn’t work in a vacuum. All the systems of the body work together- your digestion, liver, gut microbiome, your sex hormones, your adrenal glands, and your diet all influence thyroid function and therefore if you are serious about your health, you have to pay attention to the health of all of those systems if we want Vibrant- long standing health.

#3 I hope that after watching todays video or reading the transcript of this video, that you will walk away with a better understanding and the hope there is so much more that you can to to improve your health. Thyroid medication is not a cure! And for the vast majority of people out there, Thyroid medication is only a crutch. If you need to take thyroid medication, either because you had your thyroid removed, or because you have had an autoimmune disease like Hashimotos and it has permanently damaged your thyroid- the things I talked about today are still very relevant and will have a profound impact on your health. If your doctor understand these things I talked about and you approach your thyroid condition methodically, I guarantee you will see drastic changes in your life.

#4 Lastly, if you need help and you are looking to address the Big picture that I talked about today, reach out to my practice. At I have a team of health care professionals that will teach you how to strengthen and support your body so that you can avoid, decrease and sometimes even wean off unnecessary medications.

So there you go! 10 reasons your Thyroid medication is not working and why you still struggle with unresolved thyroid symptoms.

#5 Visit my website and take my Thyroid Quiz. This quiz will provide invaluable information regarding your Thyroid. If you like you can also opt in for my thyroid newsletter which will help you further understand how to improve Thyroid function. If you are looking for help you can always complete my health questionnaire. Once completed someone from my office will email you several recommendations on what we recommend as a starting point for you to become a new patient.

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