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Genetic SNP Testing (MTHFR, MTR, MTRR, COMT, AHCY)

The Methyl Detox Profile includes genetic markers or SNPs involved in methylation and homocysteine metabolism. Homocysteine is a maker of inflammation in the heart and in the brain. High homocysteine can lead to heart attacks, strokes, infertility, migraines, Brain injury, depression and more.

Price: $625

Time: Get your results 7-14 days after test. 

Specimen Collection: Cheek swab

FAQs

No- This test is done at home and comes with prepaid shipping materials and everything you need to ensure proper delivery to the lab. This is a cheek swab that evaluate the following. 

  • MTHFR
  • MTR
  • MTRR
  • COMT
  • AHCY
  • Homocysteine requires a blood draw and is an add on. Additional fees apply

Web results are posted within 7-14 business days. Our office will notify you when test results have been reported.

Yes. The kit comes with easy to follow instructions

 

Yes. Dr Hagmeyer will review the test result with you. Each test comes with a 30-45 minute post-test review/explanation.

 

One we have placed the order for the test we are unable to issue a refund.

 

Who may benefit from this test?

Individuals with any of the following diagnoses or symptoms:

  • Cardiovascular Diseases e.g. hypertension, coronary artery disease, stroke 4-10
  • Neurological Disorders e.g. depression, dementia, Alzheimer’s disease, ADD/ADHD, ASD, chronic fatigue syndrome, migraine, insomnia 7, 10-17
  • Metabolic Conditions e.g. metabolic syndrome, diabetes mellitus, kidney diseases, reduced ability to metabolize medications, multiple chemical sensitivity 10, 18-21
  • Musculoskeletal Disorders e.g. osteoporosis 10, 22
  • Eye Diseases e.g. macular degeneration 23, 24
  • Cancer e.g. colorectal, breast, and others 1, 10, 25

Learn More About The Methyl Detox Profile

About The Methyl Detox Profile

More than 50% of the population are affected by genetic mutations in the methylation pathway.

Standard MTHFR genotyping only evaluates folic acid metabolism. The Methyl Detox Profile makes it easy to understand the complicated methylation process by giving comprehensive insights into the functional status of the methylation pathway.

The Methyl Detox Profile includes genetic markers involved in methylation and homocysteine metabolism provided in a detailed lab report with personalized commentary. Additionally, continued homocysteine testing enables easy monitoring of patient progress.
Genetic variations in this pathway are associated with elevated homocysteine levels, impaired methylation processes and limited detoxification capacity. 

As a result, these SNPs (single nucleotide polymorphisms) may contribute to accelerated aging, certain chronic diseases like cardiovascular disease and neurodegenerative disorders, impaired gene-regulation, poor drug clearance, and impaired neurotransmitter metabolism. 

The primary purpose of methionine/ homocysteine balance is to ensure proper methylation by donating methyl groups for:

  • DNA methylation (gene regulation)
  • Detoxification of catecholamines from the environment
  • Drug clearance (phase II liver detoxification)
  • Homocysteine is also a precursor in the biosynthesis of L-cysteine for glutathione; glutathione is important for the detoxification of electrophilic compounds (metals).
  • Elevated serum homocysteine is a widely accepted marker for methionine/homocysteine imbalance, which is a genetically controlled process. 

Elevated homocysteine levels can lead to accelerated aging, cardiovascular disease and neurodegenerative disorders among others.

Who Should Get the Methyl Detox Profile

Comprehensive testing for methylation and detoxification

The Methyl Detox Profile gives more actionable information than MTHFR testing alone, giving you a more complete picture of your body’s methylation and detoxification. The Methyl Detox profile includes suggestions for specific nutrient needs to address with practitioner guidance.

Standard MTHFR genotyping only evaluates folic acid metabolism. Scientific research reveals that a variety of genes are involved in maintaining methionine/homocysteine balance.

Genetic variations (SNPs) in these important genes influence your methylation potential. Individual methylation is monitored using homocysteine levels. Important SNPs are included to evaluate your ability to methylate neurotransmitters, DNA, and toxins.

Who May Benefit from This Test?

Individuals with any of the following diagnoses or symptoms:

  • Cardiovascular Diseases e.g. hypertension, coronary artery disease, stroke 4-10
  • Neurological Disorders e.g. depression, dementia, Alzheimer’s disease, ADD/ADHD, ASD, chronic fatigue syndrome, migraine, insomnia 7, 10-17
  • Metabolic Conditions e.g. metabolic syndrome, diabetes mellitus, kidney diseases, reduced ability to metabolize medications, multiple chemical sensitivity 10, 18-21
  • Musculoskeletal Disorders e.g. osteoporosis 10, 22
  • Eye Diseases e.g. macular degeneration 23, 24
  • Cancer e.g. colorectal, breast, and others 1, 10, 25

What’s Being Tested

What’s Included with The Methyl Detox Profile?

Literature

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