The Cyrex Array 3X Test is the most advanced test available which can help to identify if you are celiac or sensitive to gluten.
Price: $639 (includes Testing, Consult and Meal Plan)
Time: Get your results 2-4 weeks after test.
No. This is a cash discount and includes a consultation with Dr Hagmeyer.
This test requires a blood draw. Once the test is purchased, a kit will be sent to you along with instructions and an activation code. Once your test is activated, you will be directed to a local blood draw center to have your blood draw. Specific instructions will be emailed to you regarding fasting or non fasting and if you need to stop any supplements.
Web results are posted within 7-14 business days. Our office will notify you when test results have been reported.
You will be emailed a confirmation from the lab. Within 3-5 business days, you will receive a test kit that you will take to the lab with you.
Yes. Dr Hagmeyer will review the test result with you. Each test comes with a post-test review/explanation.
One we have placed the order for the test we are unable to issue a refund.
How Do I know If Need this test? Blood tests are commonly used to evaluate a wide range of symptoms and health conditions. Here are some symptoms and situations where someone might seek blood testing:
1. Fatigue or Weakness:
Persistent fatigue or weakness can indicate anemia, thyroid dysfunction, or other underlying conditions.
2. Unexplained Weight Changes:
Sudden weight loss or gain may necessitate blood tests to assess thyroid function, hormone levels, or metabolic conditions.
3. Fever or Infection:
A fever, especially if persistent, may lead to blood tests to identify infections, such as a complete blood count (CBC) to check for signs of infection or inflammation.
4. Joint Pain or Swelling:
Symptoms of arthritis or autoimmune diseases may prompt tests for inflammatory markers or specific autoantibodies.
5. Digestive Issues:
Symptoms like diarrhea, constipation, bloating, or abdominal pain may require tests to assess liver function, pancreatic function, or to check for infections.
6. Skin Changes:
Unexplained rashes, discolorations, or persistent itching may lead to tests for allergies or autoimmune conditions.
7. Mood Changes:
Symptoms of depression, anxiety, or other mood disorders may prompt tests for thyroid function, vitamin D levels, or other hormonal assessments.
8. Menstrual Irregularities:
Irregular or heavy menstrual periods may lead to blood tests to evaluate hormone levels or assess for conditions like polycystic ovary syndrome (PCOS).
9. Chest Pain or Shortness of Breath:
These symptoms may require tests to assess heart function or oxygen levels, including tests for cardiac biomarkers.
10. High Blood Pressure:
Individuals with hypertension may undergo blood tests to assess kidney function, electrolyte balance, and to rule out underlying causes.
11. Chronic Conditions:
Patients with chronic diseases (like diabetes or chronic kidney disease) often have routine blood tests to monitor their condition and manage treatment.
12. Allergies:
Symptoms such as hives or respiratory issues may lead to blood tests for specific allergies.
13. Nutritional Deficiencies:
Symptoms like hair loss, brittle nails, or cognitive changes may prompt testing for vitamin and mineral deficiencies (e.g., vitamin B12, iron, folate).
14. Liver or Kidney Issues:
Symptoms such as jaundice (yellowing of the skin and eyes), dark urine, or swelling in the legs may require liver or kidney function tests.
Your Personalized Gluten Sensitivity Profile and Consult Includes:
- Gluten Sensitivity Testing Cyrex Array 3
- Follow up consult to discuss test results with Dr Hagmeyer or Nutritionist
- Meal Plan Gluten free diet if necessary.
Celiac Disease Or Gluten Sensitivity
If you think you are reacting to gluten how do you know if it is celiac disease of gluten sensitivity?
Or if you get bloated and gassy after eating bread it may not be the gluten at all, you maybe reacting because wheat is a high FODMAP food.
Gluten can cause brain fog and other cognitive symptoms, but if you get neurological symptoms every time you eat bread it may also be the preservatives in flour that are causing the problems.
Doing a month long elimination of gluten can help to identify if you have an issue with gluten containing foods.
What happens if you feel good for cutting out gluten?
Does that mean that you have to avoid gluten forever?
If you want to identify why you are having issues, or if you would like to know if you need to cut out gluten 100%, or simply reduce gluten containing foods (or avoid flour products with preservatives) then the Cyrex Array 3X test is the best option.
What is gluten sensitivity?
Gluten sensitivity or Gluten intolerance is when your body cannot tolerate one or more of the proteins found in grains like wheat, barley, and rye. Gluten intolerance is also called non-celiac gluten sensitivity. It’s not the same as celiac disease or a wheat allergy. Gluten can be found in common foods and drinks, including pasta, cereal and beer. Gluten can also be in things like vitamins, cosmetics and even certain medications.
The symptoms of Gluten Sensitivity or Gluten intolerance are:
- Abdominal pain.
- Anemia.
- Anxiety.
- Bloating or gas.
- Brain fog, or trouble concentrating.
- Depression.
- Diarrhea or constipation.
- Fatigue.
The symptoms above could be caused by gluten or they cold be caused by another food sensitivity, gut infections, stress, low digestive enzymes or a number of other reasons.
Are Gluten Intolerance and Celiac Disease The Same Thing?
Gluten intolerance and celiac disease are different. People with celiac disease have an autoimmune response to gluten. This means their bodies try to fight against gluten as if it were a virus. This reaction causes inflammation and damage to their digestive tracts. Celiac disease is the result of an abnormal gene. People with celiac disease also have high levels of certain antibodies in their blood, which are substances that fight gluten.
Gluten sensitivity and celiac disease cause a lot of the same symptoms. But people with gluten sensitivity don’t have an abnormal gene or antibodies in their blood.
What is Celiac disease?
Celiac disease is a well-recognized medical condition in which gliadins (gluten proteins found in wheat, barley and rye) cause an autoimmune reaction which destroys the lining of the small intestine.
This can lead to a wide range of digestive symptoms and malabsorption of nutrients.
However, it is possible that some celiac patients have no digestive symptoms, even though their body is still being damaged, this is known as silent celiac disease.
Some people may have mild digestive symptoms but experience neurological and psychiatric symptoms, or skin issues instead of the classic digestive system problems.
Simply put, the Cyrex Array 3 will rule out if you have a wheat allergy or gluten intolerance.
Does a gluten-free diet have health risks?
Research shows that a gluten-free diet may increase your risk of:
- Hyperglycemia (high blood sugar) or Type 2 diabetes.
- Nutritional deficiencies such as too little fiber.
This is why before you embark on a gluten free diet that you consult our office and work with one of nutritional therapists.
Why Do The Cyrex Array 3X Test
Have you been tested for celiac disease only to be told that everything is fine?
The standard celiac test measures gliadin antibodies and transglutaminase-2 IgG and IgA , if you test positive to transglutaminase then you have celiac disease.
However, if you test negative on the standard celiac test that does not 100% rule out celiac disease as there is transglutaminase markers that they do not test for.
This is where the Cyrex array 3 test from Cyrex labs comes in, this can help to know exactly why you are reacting to gluten and if you need to minimize or avoid 100%
Cyrex Laboratories array 3 is a blood test which aids in an accurate analysis of gluten and wheat to see if you are reacting, even if the standard test shows you are fine.
The Cyrex Array 3 is a blood test that measures antibody production against eight wheat proteins and peptides and three essential enzymes. It is the only test available with comprehensive panels for establishing which component of the wheat protein challenges your immune system.
If your immune system is challenged this can lead to problems such as allergies, asthma, and autoimmune disease.
If you have an autoimmune disease, your immune system will attack healthy cells in your body by mistake. Other immune system problems will also happen when your immune system does not work correctly.
The Cyrex Array 3 also includes various tissue transglutaminases, which indicate tissue damage to various tissues in the body including neural tissue.
A positive reaction to Transglutaminase 2, 3, or 6 IgA would indicate celiac disease.
Gluten Sensitivity Symptom Check list
- Depression and Anxiety
- Bloating, Constipation, Diarrhea, Gas
- Brain Fog Skin conditions such as Eczema, Psoriasis, dermatitis herpetiformis (DH), mouth sores, Canker sores,
Fatigue
- Spinal and Joint pain
- Weakened immune response and Autoimmune Disease
- Migraines and Headaches
- Hormone Imbalances
- Endocrine disorders- (Thyroid, Adrenal, Sex Hormone imbalances)
- Vitamin and mineral imbalances (Iron, Ferritin, Vitamin D, Zinc,)
About Gluten Illness & Intolerance
We now know that gluten illness is a spectrum of disorders rather than all about coeliac disease.
You can have 4 main types:
- Gluten Classical IgE Allergy – rare but does occur
- Gluten Malabsorption – lack of enzymes to break it down, although I don’t think that occurs without a larger gluten problem personally; it’s a clue.
- Coeliac Disease – the autoimmune attack on the villi in the gut and..
- Non-Coeliac Gluten Sensitivity (NCGS) – every bit as serious as Coeliac Disease, an inflammatory and sometimes autoimmune attack anywhere in the body. People with an ‘intolerance’ ie. a delayed reaction to gluten would also come under this category. This is far more prevalent than coeliac disease.
This makes testing for gluten related disorders somewhat complex. In essence, mainstream medicine is very slow at changing and 99% of health professionals still think about and look only for coeliac disease markers. To get an official diagnosis on your health records, it is likely that you need to go through the mainstream coeliac testing process so it’s best to start with that.
Dr Marsh, who invented the coeliac scoring system, is frustrated by the medical profession who, he says, still believe coeliac disease is a disease of the small intestine. It is not, he explains:
“Gluten sensitivity is a spectrum and is more likely an immunological response involving T lymphocytes in the mesenteric system to gluten in ways we don’t yet fully understand.”
Most Common Signs of Gluten Intolerance or Gluten Sensitivity
People typically shrug off the possibility of a gluten sensitivity by saying, “I don’t have any digestive problems.” Little do they know that gluten produces digestive symptoms in only a minority of people (1 out of 8). For the majority gluten damages the brain, the heart, the skin, the respiratory tract, or the joints. Even if your doctor has told you that you don’t have celiac disease, you CAN still be gluten sensitive.
Dr Peter Green, Director of the Celiac Disease Center at Columbia University says that
“60-70% of the people he sees who think they have coeliac disease don’t but they are actually gluten-sensitive.”
Test It Instead of Guessing
If you experience any of the above symptoms frequently, you may very well be intolerant to the foods you are eating. It is time to get it tested.
The Power of Knowing
There is a new paradigm in health and medicine – personalization. Health can be improved and maintained by knowing how food plays a role in your body. The Cyrex Array 3 Panel enables you to take advantage of leading technology to create a personalized nutrition plan resulting in benefits that can be seen and felt.
The results from the Cyrex Array 3 Panel can help determine which gluten subfractions may trigger unwanted inflammation. The personalized nutrition plan based on your immune response can assist with food choices that are better for your health and well-being. When complying with the Gluten Sensitivity Test results, many clinical symptoms associated with food sensitivity may be substantially improved or possibly prevented altogether.
Why I only Recommend Cyrex Labs for Testing
Researchers have proven that 50% of patients diagnosed with Celiac disease do not respond to the one protein being assessed in the conventional tests, instead they react to one or more of the other gluten proteins that are not measured in those conventional tests.
Additionally, more labs are switching to only offering deamidated gliadin because it is more sensitive for Celiac disease.
Unfortunately, the larger percentage of the population, Non-Celiac Gluten Sensitive patients, has been shown to be more reactive to native gliadin.
Cyrex Labs is the only lab that measures both native and deamidated gliadin along with other gluten family proteins, the opioid peptides from both gluten and wheat, the lectin portion of wheat and wheat as a whole.
Because not every person’s gluten reactivity manifests as Celiac disease, Cyrex Labs measures antibodies to multiple transglutaminases to capture those patients whose gluten reactivity manifests as skin disorders or neurological complaints.
NCGS can be more severe.
The other issue is that there are far more people suffering with the other forms of gluten related disorder, especially NCGS (non-coeliac gluten sensitivity) and, in fact, NCGS can be every bit as severe as coeliac disease and worse in many cases. NCGSs are known to be more sensitive to gluten, to react more strongly to it and to react to much smaller amounts. They also tend to be more reactive to other grains, not just the gliadin involved in coeliac disease, but especially the ubiquitous corn which literally turns up in everything.
Professor Umberto Volta advises:
“If you have brain fog, fatigue, headache, arthralgia, myalgia, skin diseases, IBS, chronic anaemias, mouth ulcers, alopecia, Autoimmune thyroiditis, Autoimmune gastritis, nickel allergy, multiple food sensitivity, lactose intolerance or fructose intolerance, consider gluten sensitivity, especially NCGS.”
Antigens Tested
- Wheat IgG
- Wheat IgA
- Wheat Germ Agglutinin IgG
- Wheat Germ Agglutinin IgA
- Native + Deamidated Alpha-Gliadin-33-mer IgG
- Native + Deamidated Alpha-Gliadin-33-mer IgA
- Alpha-Gliadin-17-mer IgG
- Alpha-Gliadin-17-mer IgA * (Typically what gets tested)
- Gamma-Gliadin-15-mer IgG
- Gamma-Gliadin-15-mer IgA
- Omega-Gliadin-17-mer IgG
- Omega-Gliadin-17-mer IgA
- Glutenin-21-mer IgG
- Glutenin-21-mer IgA
- Gluteomorphin+Prodynorphin IgG
- Gluteomorphin+Prodynorphin IgA
- Gliadin-Transglutaminase Complex IgG
- Gliadin-Transglutaminase Complex IgA
- Transglutaminase-2 IgG
- Transglutaminase-2 IgA
- Transglutaminase-3 IgG
- Transglutaminase-3 IgA
- Transglutaminase-6 IgG
- Transglutaminase-6 IgA
Notice all the markers that don’t get checked on normal testing.
How it works
A small sample of your blood is sent to the laboratory overnight. Upon receiving the sample, the blood goes through a multi-step quality assurance process. After testing, the results are presented in a clear and easy to read color-coded format.