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  • Affordable Treatment

IBSchek® – The First Clinically Validated Blood Test for Irritable Bowel Syndrome with Predominant Diarrhea (IBS-D) and Mixed Symptoms (IBS-M).

Now only $420 with available at-home Capillary Collection Kit!*

IBS Check Test and Consult For IBS-D and IBS-M

 

What is IBScheck test?

IBSchek is a simple ELISA*-based blood test that is highly predictive of an IBS diagnosis based on the presence of two antibodies—anti-CdtB and anti-vinculin. In a study of more than 2,500 patients conducted in 180 centers around the U.S., IBSchek was found to be more commonly positive in IBS with diarrhea (IBS-D) or IBS with mixed symptoms (IBS-M) compared to patients with Crohn’s disease, ulcerative colitis, and celiac disease. IBSchek is the first clinically validated blood test to confirm a diagnosis of either IBS-D or IBS-M. *ELISA = enzyme-linked immunosorbent assay.

What does the test measure?

IBSchek was developed based on the scientific discovery that irritable bowel syndrome often results from a previous episode of gastroenteritis. IBSchek tests for the presence of antibodies in the blood that were created by alterations in the intestinal microbiota resulting from acute gastroenteritis. It detects levels of an antibody to a toxin called CdtB (cytolethal distending toxin B), as well as vinculin, a human protein commonly found in nerves and the lining of the gut. While the test is more specific for anti-CdtB, the anti-vinculin component suggests that irritable bowel syndrome may be an autoimmune disease. The two levels enable a differential diagnosis of IBS from inflammatory bowel disease (IBD).

IBS and SIBO-Is there a connection?

It is now known, based on extensive human and animal research, that acute gastroenteritis leads to IBS. In animal studies, infection with campylobacter jejuni (C. jejuni) caused small intestinal bacterial overgrowth. C. jejuni infection also leads to the production of the anti-CdtB and anti-vinculin antibodies detected by IBSchek. In the same animal studies, antibody levels were related to the number of infections the animals experienced. However, irrespective of the number of infections with C. jejuni, bacterial overgrowth was more closely related to the antibodies than the number of infections.

Is IBScheck test for people with diarrhea and mixed IBS?

IBSchek has been validated in diagnosing irritable bowel syndrome associated with diarrhea and mixed symptoms. Published studies have determined the cost savings—both direct and indirect—to the patient and healthcare system from receiving a faster diagnosis.

Does IBScheck suggest what treatment is best for me?

A positive IBSchek can confirm that you have IBS-S or IBS-M and that your disease is an organic condition based on the presence of validated biomarkers. IBSchek does not offer insight into which treatment is best for your irritable bowel syndrome patient. If this test is positive, Dr Hagmeyer may recommend additional testing.

IBSchek Capillary Collection Kit

The IBSchek Capillary Collection Kit offers direct patient access, simple and safe sample collection, free shipping included, and easy-to-understand results in just a few days.**

The IBSchek Capillary Kit is one of the tests we use to help our patients quickly and reliably diagnose diarrhea-predominant or mixed-symptom IBS (IBS-D/M). Symptoms of this chronic ailment often occur following an incident of acute gastroenteritis (food poisoning).

IBSchek is performed in a CLIA-certified laboratory and results can provide you and your health care provider with actionable clinical data and a better understanding of your health.

The IBSchek Capillary Kit Includes:

  • Test Requisition Form;
  • Easy-to-follow Instructions for Use;
  • Sterile Collection and Return Materials; and
  • Pre-Paid Return Shipping Label

Does testing include a consult with Dr Hagmeyer?

  • Yes. Every test ordered through the DrHagmeyer.com website includes the following
  • The ordering of the test kit on your behalf
  • Interpretation of testing
  • 30 minute consult with to discuss lab testing findings and recommendation on what to do next.
  • Return shipping to lab

About CDI

Commonwealth Diagnostics International, Inc. is a CLIA-certified independent laboratory operating out of a state-of-the-art laboratory located in Salem, Massachusetts. In lieu of expensive, invasive, and inaccessible diagnostic methods, CDI provides non-invasive and cost-effective tools to empower patients by providing meaningful information about their gastrointestinal condition.

IBS Check Test and Consult For IBS-D and IBS-M 5About IBSchek

IBSchek is a proprietary blood test for IBS based on the scientific findings of a 2500+ patient clinical trial which showed that anti-vinculin and anti-CdtB are effective biomarkers for the diagnosis of diarrhea-predominant or mixed-symptom IBS. Irritable Bowel Syndrome (IBS) is the most common functional gastrointestinal syndrome in the U.S. It is estimated that up to 45 million people, or 10-15% of the American population, suffer from IBS.

FAQ

Q.  What is IBSchek?

IBSchek is a proprietary blood test for IBS based on the scientific findings of a 2500+ patient clinical trial which showed that anti-vinculin and anti-CdtB are effective biomarkers for the diagnosis of diarrhea-predominant or mixed-symptom IBS.  Click here to read published clinical data validating IBSchek for diagnosing IBS-D and IBS-M.

Q. What is an IBSchek capillary collection kit?

IBSchek can now be performed using our at-home capillary collection kit.  The kit includes the test requisition form, easy-to-follow instructions for use, sterile collection and return materials, and pre-paid return shipping materials.  A detailed instructional video is located on our website that provides step-by-step instructions on how to collect a sample at home.  Click here to order a capillary collection kit online.

Q. Do I have to do this test at home or can I go to a laboratory. 

For patients that do not wish to use CDI’s simple at-home capillary kits and instead want to use their own phlebotomy service, CDI will provide complimentary sample return shipping supplies upon request. Please contact [email protected] to order return shipping supplies.

Q.  How quickly can I receive results from your lab?

When the sample arrives at our laboratory, it will be analyzed within 24-48 hours.  When our office has been notified of your test Results and Dr Hagmeyer has reviewed them, you will be contacted to schedule a 30 minute consult with Dr Hagmeyer or one of his associates.  This const of of the consult is included in the cost of the testing.

Published Clinical Data Validating IBSchek for Diagnosing IBS-D and IBS-M

“Development and Validation of a Biomarker for Diarrhea-Predominant Irritable Bowel Syndrome in Human Subjects” Mark Pimentel, Walter Morales, Ali Rezaie, et al. PLoS One. 2015; 10:e0126438.

“Assessment of Anti-vinculin and Anti-cytolethal Distending Toxin B Antibodies in Subtypes of Irritable Bowel Syndrome.” Rezaie A, Park SC, Morales W et al. Dig Dis Sci. 2017 Jun; 62(6):1480-1485.

“Clinical experience with the use of anti-CdtB and anti-vinculin antibodies in patients with diarrhea in Mexico.” Schmulson M, Balbuena R, Corona de Law C. Rev Gastroenterol Mex. 2016 Oct – Dec;81(4):236-239.

“The Utility of Measuring Anti-Cytolethal Distending Toxin B and Anti-Vinculin Antibodies in a Tertiary Care Motility Practice: A Free-Range Experience.” Pourmorady J, Rezaie A, Pimentel M, et al. Gastroenterology. 2016;4 (Suppl1): S-230.

**Result data should be interpreted with the help of a qualified health care provider and all clinical decisions should consider other symptoms and health factors in disease diagnosis and management.

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The entire contents of this website are based upon the opinions of Dr. Richard Hagmeyer unless otherwise noted. Individual articles are based upon the opinions of the respective author, who retains copyright as marked. The information on this website is not intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice. It is intended as a sharing of knowledge and information from the research and experience of Dr. Hagmeyer and his community. Dr. Hagmeyer encourages you to make your own health care decisions based upon your research and in partnership with a qualified healthcare professional. These statements have not been evaluated by the Food and Drug Administration. Dr. Hagmeyer products are not intended to diagnose, treat, cure or prevent any disease. If you are pregnant, nursing, taking medication, or have a medical condition, consult your physician before using any products. Copyright © 2021 Dr. Hagmeyer · All Rights Reserved · Powered by drhagmeyer.com

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