We know how frustrating it can be to struggle with Histamine Intolerance and MCAS Symptoms. If you are like most patients you have been on the medical merry go round, bouncing from one doctor to the next. There are many reasons for Histamine Intolerance and MCAS. Let us provide you with the answers you are searching for.
In addition to the symptoms listed above, excess histamine can make some existing conditions worse. Eczema is an example. Eczema is an inflammatory condition in the skin, sometimes called atopic (allergic) dermatitis. When high histamine foods are consumed, people with less than efficient histamine tolerance may experience an increase in the severity of their eczema.
The complexity of histamine intolerance extends to the interaction between histamine, estrogen and progesterone in the female body. Mast cells are a key factor underlying these interactions, with the presence of both estrogen and progesterone receptors on mast cells. The binding of estrogen to mast cell receptors stimulates the expression of H2 and H3 receptors, and induces rapid histamine degranulation, synthesis and release. Estrogen can also influence endogenous histamine levels by down regulating DAO activity. This ultimately leads to high histamine levels in the body.
Having excess histamine goes way above and beyond your typical allergy symptoms. Excessive histamine can also wreck havoc on the brain. Histamine has been shown to play a pivotal role in many psychiatric disorders such as depression, schizophrenia, anxiety. Because histamine plays a role in wakefulness of the brain, too much histamine can overstimulate the brain leading to anxiety and insomnia as well as restlessness. Any unbalance in the chemical makeup of your brain is bound to cause unwanted effects. These side effects can vary drastically from person to person depending on what Histamine receptor (H1,H2,H3,H4) is stimulated. Brain fog, fatigue, and anxiety are all too common for people who suffer with MCAS and histamine intolerance.
SIBO is an intestinal motility disorder that leads to an overgrowth of good or bad bacteria in the small intestine, where few bacteria belong. There are many causes of SIBO however diets high in sugar and refined carbs, antibiotics or other medications that disrupt your delicate microbiome leading to symptoms such as bloating, gas, constipation or diarrehea.
Histamine receptors are found all throughout the body and as a result, histamine intolerance affects each of us in different ways. The symptoms that present themselves vary based on which of the four histamine receptors are being activated (H1, 2, 3, 4), and where. In the heart, histamine functions as a vasodilator, meaning that it widens our blood vessels, and therefore there is less resistance to blood pumping through the body this causes a drop in blood pressure.
The concept of the “histamine bucket” is a way to visualize this accumulation. It is often depicted as a metaphorical bucket that represents the individual’s capacity to handle and tolerate histamine.
When someone consumes or is exposed to histamine-rich foods, such as fermented products, aged cheeses, or alcohol, or when they experience other triggers like stress, Mold toxins, Genetic Mutations in DAO enzyme, Leaky Gut, Estrogen Dominance, or any of the things you see below, their histamine levels may rise.
As histamine accumulates in the body, it can exceed the individual’s capacity to break it down and eliminate it, causing symptoms of histamine intolerance.
Once the “histamine bucket” overflows, individuals may experience symptoms such as headaches, hives, digestive issues, nasal congestion, itching, flushing, or other allergic-like reactions.
These symptoms can vary in severity and can impact different systems of the body.
For people with histamine intolerance, symptoms tend to increase as the day goes on. Symptoms also worsen if multiple high histamine foods are consumed on the same day or close together. Remember the bucket analogy I mentioned above?.
Symptoms happen when the bucket fills up due to the combined effect of natural histamine and the histamine consumed in food.
The body’s natural source of histamine can be difficult to control without testing and identifying the cause, but the dietary intake is manageable.
Determining what foods are problematic is an initial step for improving your Histamine intolerance/MCAS.
For this reason, a histamine intolerance diet and treatment plan looks different for everyone. Luckily, there are some general tips which I have included in this Ebook to get you started. Also, the food lists included in this ebook, is a place to start. They contain foods to avoid or include to decrease the risk of developing symptoms.
Histamine causes a sudden and rapid inflammatory response, setting off an alarm within the immune system that invaders are present. As a result, white blood cells are called upon to swiftly identify and eliminate the foreign bodies. It is the quick flood and build up of histamine that can cause symptoms such as headache, itchiness, flushed face, and overall feeling inflamed and uncomfortable.Histamine works through your bloodstream so high levels that aren’t broken down can potentially harm not only your gut but your lungs, brain, skin, and cardiovascular system. It is for this reason that symptoms can vary from person to person.
WHY YOU SHOULD CONSULT WITH A DOCTOR DR HAGMEYER
We know that successfully managing Histamine Intolerance and MCAS takes more than just taking antihistamines. That’s why we focus on the whole person and the root causes behind your symptoms. Once you download my free E-book, on the Next page, you will gain access to a several videos that I think you will find incredibly helpful. Treating Histamine intolerance and MCAS is complex. If you are not feeling better, don’t beat yourself up. Successful treatment and management require a whole person approach. Start today by downloading the free histamine E-book and watch the videos on the next page.
Download this E-book today. Then watch the videos on the next page.